Caryophyllene: Spicy, sweet, woody, clove, camphor, perppery.

Found in Black PepperĀ (15-25%), Clove (10-20%), and Cotton (15-25%). Binds weekly to CB2 receptor. As a topical preparation, it is one of the components of clove oil, and anti-inflammatory and analgesic treatment for toothache. In large amounts, it's a calcium and potassium ion channel blocker. As a result, it impedes the pressure exerted by heart muscles. Since THC itself has no fragrance, drug dogs are trained to find one, very odorous molecule called Caryophyllene-epoxide.